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List of Diseases and their Pathognomonic (Hallmark) Signs

I have created this list when I was reviewing for my Nurse Licensure Examination. Pathognomonic sign is also known as hallmark sign. This is a kind of unique sign seen on patients having these diseases. These are used to easily distinguish one disease from another. However, these signs are not the basis for diagnosing clients. Laboratory tests are still needed before diagnosing clients. If you have anything to add on the list, please write it in the comment box. Thanks! 



    Atrial Septal Defect-
high pitched diastolic murmur/systolic click
    Patent Ductus Arteriosus-
gibson murmur/machinery like murmur
    Coarctation of Aorta-
increase b.p. in upper extremities and
decrease b.p. in lower extremities
   Aortic Stenosis-
hypotension
    Pulmonic Stenosis-
systolic ejection murmur
   Tetralogy of Fallot-
"tet spell"/hypercyanotic
    Kawasaki Disease (acute phase)-
strawberry tongue
   Hydrocephalus-
sunset eyes
    Intussusception-
currant jelly stool
  Hirschprung disease-
ribbonlike stol
    Measles-
kopliks spots
      5th disease-
rosy cheek appearance
      Pertussis-
whooping cough
       Cholera-
profuse rice watery stool
    Shigellosis-
bloody diarrhea
     Hypocalcemia-
tetany
     Hypercalcemia-
paralysis
    Hyperkalemia-
muscle twitch
Hypermagnesemia-
decrease deep tendon reflex
     Compartment syndrome-
paresthesia
      Fat embolism-
petechiae in trunk
    Gouty arthritis-
swelling at big toe
   Rheumatoid arthritis-
morning stiffness
     Osteoarthritis-
pain after activity
   Hepatic cirrhosis-
hypotension,tachycardia,tachypnea
 Hypovolemic shock-
narrowed pulse pressure
  Decrease bile in GIT-
steatorrhea
  Hepatic encephalopathy-
asterexis
   Meningitis-
nuchal rigidity
  Gonorrhea-
greenish diarrhea
 Syphilis-
painless ulceration
   Trichomoniasis-
white-greenish odorous discharge
   Gardenerilla-
grayish-yellowish discharge
Genital herpes-
very painful vesicular lesion
  Typhoid fever-
rose spots in chest
 Rabies-
laryngospasms
Diphtheria-
pseudomembrane color is grayish black
German measles-
lymphadenopathy
  Roseola-
macular rash
  Flat bone injury-
bleeding
Long bone injury-
fat globules/embolism